Benzaldehyde, 2-fluoro-3-methoxy- - Names and Identifiers
Benzaldehyde, 2-fluoro-3-methoxy- - Physico-chemical Properties
Molecular Formula | C8H7FO2
|
Molar Mass | 154.14 |
Density | 1.192±0.06 g/cm3(Predicted) |
Melting Point | 47-51 °C (lit.) |
Boling Point | 239.9±20.0 °C(Predicted) |
Flash Point | 110°C |
Vapor Presure | 0.0391mmHg at 25°C |
Appearance | White to Yellow Crystalline Solid |
Storage Condition | Inert atmosphere,2-8°C |
Sensitive | Air Sensitive |
Refractive Index | 1.525 |
MDL | MFCD03411962 |
Benzaldehyde, 2-fluoro-3-methoxy- - Risk and Safety
Risk Codes | R22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
R43 - May cause sensitization by skin contact
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
HS Code | 29130000 |
Hazard Note | Irritant/Keep Cold |
Benzaldehyde, 2-fluoro-3-methoxy- - Introduction
2-Fluoro-3-methoxybenzaldehyde is an organic compound with the formula C8H7FO2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-Fluoro-3-methoxybenzaldehyde is a white crystalline solid.
-Solubility: It is soluble in some organic solvents, such as ethanol and dimethylformamide.
-Melting point: Its melting point is about 60-62 degrees Celsius.
-Molecular structure: Its molecule contains a methoxy group and a fluorine atom, as well as a benzene ring and a formaldehyde group.
Use:
-2-fluoro-3-methoxybenzaldehyde can be used as intermediates and reagents in organic synthesis.
-It is commonly used in the field of pharmaceutical and pesticide research and development, as an important raw material for synthetic drugs and pesticides.
Preparation Method:
-A common method for preparing 2-fluoro-3-methoxybenzaldehyde from methoxybenzophenone is through fluorination. First, in the presence of hydrofluoric acid, methoxybenzophenone is reacted with fluoride ions to obtain 2-fluoro-3-methoxybenzophenone. Then, 2-fluoro-3-methoxybenzophenone is converted into 2-fluoro-3-methoxybenzaldehyde through a reaction such as reduction or oxidation.
Safety Information:
-2-Fluoro-3-methoxybenzaldehyde Care should be taken to prevent contact with skin, eyes and respiratory tract.
-Wear appropriate protective equipment such as gloves, safety glasses and dust mask during operation.
-Maintain a well-ventilated laboratory environment and avoid inhaling its vapors.
-When handling the substance, follow proper laboratory practices and safe operating instructions.
Please note that proper safe handling and laboratory procedures should always be followed when using and handling chemicals.
Last Update:2024-04-09 21:01:54